Calorie restriction: mTOR, sirtuins and autophagy
mTOR, sirtuins and autophagy are studied in nutrient responses and aging; these mechanisms are not, by themselves, human dietary recommendations.
Scientific sources and reference guidelines
A selection of scientific references and guidelines on Calorie restriction: mTOR, sirtuins and autophagy. The list is not exhaustive and may be updated over time.
- Johnson et al., Nature (2013) — PMID 23325216 — Review of mTOR in aging and age-related disease; mechanistic evidence comes largely from model organisms.
- Guarente, Genes & Development (2013) — PMID 24115767 — Review of sirtuins and calorie restriction; it synthesizes molecular and preclinical findings without establishing an anti-aging diet therapy.
- Ohsumi, Cell Research (2014) — PMID 24366340 — Historical and molecular account of autophagy, including ATG gene discoveries and responses to nutrient deprivation.
- Dilova et al., Cell and Molecular Life Sciences (2007) — PMID 17260088 — Review of nutrient-sensing pathways involved in calorie restriction; mechanisms studied mainly in experimental systems.
The listed sources represent the main references on which Cibus AI is trained and updated. The list is constantly evolving and is not exhaustive. Cibus AI is a support tool and does not replace clinical, professional or ethical judgment: every decision remains the full and exclusive responsibility of the professional.
Frequently asked questions
What does the evidence say about Calorie restriction: mTOR, sirtuins and autophagy?
This page summarizes selected studies and guidelines on Calorie restriction: mTOR, sirtuins and autophagy. Evidence types and certainty vary; no single source proves effectiveness for every population or clinical situation.
Which sources does Cibus AI rely on for Calorie restriction: mTOR, sirtuins and autophagy?
Cibus AI relies on clinical guidelines, international standards and reference scientific literature for Calorie restriction: mTOR, sirtuins and autophagy, listed on this page and continuously updated.
Does Cibus AI replace clinical judgment?
No. Cibus AI is a support tool: every decision remains the full and exclusive responsibility of the professional.
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