Scientific sources and guidelines

What Cibus AI is based on

Cibus AI is trained and continuously updated on clinical guidelines, international standards and leading scientific literature. Below are the main sources, organized by area.

Document under continuous development and updating
  • SACN – Scientific Advisory Committee on Nutrition (UK), Dietary Reference Values, incl. specific populations (children, elderly, pregnancy)
  • PHE / OHID – Eatwell Guide and UK dietary recommendations
  • EFSA (European Food Safety Authority)
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  • Type 1 / Type 2 diabetes – ADA, AMD-SID
  • Obesity – EASO, ADI
  • Dyslipidemia – ESC / EAS
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  • Tirzepatide (Mounjaro) – SURMOUNT-1/2/3/4 trials (NEJM, 2022-2023)
  • Semaglutide (Ozempic / Wegovy) – STEP trials (NEJM, 2021)
  • ESPEN Guidelines on Clinical Nutrition in Obesity – protein target β‰₯1.2 g/kg
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  • ADA – Standards of Care in Diabetes (2024)
  • EASD/ADA – Consensus Report on managing hyperglycemia in T2
  • Carbohydrate counting – ISPAD/ADA
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  • ATA – Guidelines on hypothyroidism
  • Selenium and autoimmune thyroiditis – systematic reviews
  • Iodine and thyroid function – WHO
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  • ESHRE/ASRM – International Evidence-based Guideline PCOS (2023)
  • Low-glycemic diet and insulin resistance
  • Inositol in PCOS – meta-analyses
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  • ACG – Guidelines on celiac disease
  • Gluten-free diet – Codex Alimentarius standard
  • Non-celiac gluten sensitivity – position papers
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  • Eating disorders – NICE guidelines (UK)
  • BEAT – UK eating disorder charity clinical resources
  • RCPsych – Royal College of Psychiatrists (UK)
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  • ISSN – International Society of Sports Nutrition
  • IOC consensus on sports nutrition
  • ACSM – American College of Sports Medicine
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  • Guidelines on carbohydrates, hydration and carb-loading (IJSNEM, IOC)
  • Iron and vitamin D in endurance sport
  • World Athletics (IAAF) – nutrition consensus
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  • ISSN – position stands on bulking, cutting and refeeding
  • Body recomposition and strength training (JSCR)
  • NSCA – National Strength and Conditioning Association
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  • ESPEN – clinical nutrition and sarcopenia
  • ESPEN – enteral nutrition, hospital and home
  • ESPEN – parenteral nutrition, hospital and home
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  • ESPGHAN (complementary feeding, breastfeeding, pediatric obesity)
  • RCPCH – Royal College of Paediatrics and Child Health (UK)
  • AAP – American Academy of Pediatrics
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  • ESPEN oncology nutrition
  • Cancer Research UK / NCRI – National Cancer Research Institute (UK)
  • WCRF / AICR – World Cancer Research Fund
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  • Sarcopenia – EWGSOP2
  • Malnutrition – MNA, MUST, NRS-2002
  • ESPEN elderly
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  • EAACI (food allergies)
  • ESPGHAN (cow's milk protein allergy)
  • WAO – World Allergy Organization
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  • RCOG – Royal College of Obstetricians and Gynaecologists (UK)
  • NICE – antenatal and maternal nutrition (UK)
  • ACOG
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  • Thyroid and nutrition – ETA
  • PCOS – ESHRE / ASRM
  • Osteoporosis – IOF, SIOMMMS
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  • Cardiology – ESC
  • Pulmonology – GOLD (COPD)
  • Rheumatology – EULAR
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  • ISNPR – International Society for Nutritional Psychiatry Research
  • Lancet Psychiatry / BMJ (SMILES trial)
  • ESCAP – European Society for Child and Adolescent Psychiatry
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  • ECCO – European Crohn's and Colitis Organisation
  • ESPEN
  • AGA – American Gastroenterological Association
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  • ESPGHAN
  • AAP – American Academy of Pediatrics
  • WHO – newborn nutrition
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  • SCCM – Society of Critical Care Medicine
  • ASPEN
  • ESPEN
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  • ESPEN – dedicated position paper
  • AGA – American Gastroenterological Association
  • UEG – United European Gastroenterology
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  • NPUAP / EPUAP / PPPIA
  • EWMA – European Wound Management Association
  • ESPEN – nutrition and wounds
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  • ADA – American Diabetes Association
  • IADPSG
  • ACOG – American College of Obstetricians and Gynecologists
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  • ESHRE – European Society of Human Reproduction and Embryology
  • ASRM – American Society for Reproductive Medicine
  • FIGO
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  • NOVA classification (Monteiro et al.)
  • WHO
  • EFSA
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  • Emerging literature on long COVID and nutrition
  • WHO – clinical management of COVID-19
  • NICE – long-term effects of COVID-19
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  • ECTRIMS (multiple sclerosis)
  • MDS – Movement Disorder Society
  • EAN – European Academy of Neurology
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  • WHO
  • EASL
  • NIAAA – National Institute on Alcohol Abuse and Alcoholism
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  • NATO – operational nutrition panel
  • USARIEM – US Army Research Institute of Environmental Medicine
  • IOC – consensus on altitude and heat
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  • ASMBS – American Society for Metabolic and Bariatric Surgery: Integrated Health Nutritional Guidelines for the Surgical Weight Loss Patient – 2016 Update: Micronutrients, published in 2017
  • ASMBS / IFSO: Indications for Metabolic and Bariatric Surgery (2022)
  • SICOB – Italian Society of Obesity and Metabolic Surgery: Italian guidelines and recommendations for multidisciplinary care and follow-up after metabolic and bariatric surgery
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  • ESPEN – clinical nutrition in surgery and perioperative care
  • ESPEN – pancreatic disorders and exocrine pancreatic insufficiency
  • Nutrition after gastrectomy: early and late dumping syndrome, vitamin B12 and iron supplementation
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  • Academy of Nutrition and Dietetics
  • The Vegan Society / Vegetarian for Life (UK)
  • DGE – German Nutrition Society (2024 position)
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  • EASL
  • BASL – British Association for the Study of the Liver (UK)
  • AASLD
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  • IDDSI
  • ESSD
  • ASHA – American Speech-Language-Hearing Association
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  • IMS – International Menopause Society
  • EMAS
  • NAMS – North American Menopause Society
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  • IOC – RED-S consensus
  • ACSM – Female Athlete Triad position stand
  • BASEM – British Association of Sport and Exercise Medicine
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  • ISAPP
  • WGO – World Gastroenterology Organisation
  • AGA – microbiome guidelines
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  • EFSA – health claims
  • ISSN
  • ODS / NIH – Office of Dietary Supplements
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  • International Ketogenic Diet Study Group
  • ILAE (epilepsy)
  • AAN – American Academy of Neurology
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  • EAT-Lancet Commission
  • FAO / WHO
  • IPCC – food systems and climate
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  • ISNN – International Society of Nutrigenetics/Nutrigenomics
  • NuGO – Nutrigenomics Organisation (Europe)
  • EFSA – nutrigenomics and health claims
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  • Literature on circadian rhythms and time-restricted eating
  • SRBR – Society for Research on Biological Rhythms
  • ESRS – European Sleep Research Society
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  • AAD – American Academy of Dermatology
  • EADV – European Academy of Dermatology and Venereology
  • BAD – British Association of Dermatologists
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  • AHA β€” American Heart Association β€” Dietary guidelines for cardiovascular prevention; recommendations on saturated fat, sodium, added sugars and cardioprotective patterns.
  • ACC β€” American College of Cardiology β€” Documents on nutrition and heart failure, including sodium and fluid control; published jointly with AHA.
  • DASH Diet β€” NHLBI β€” Evidence-based dietary protocol for hypertension and cardiovascular risk; the DASH trials are among the most cited RCTs in nutrition.
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  • ERS β€” European Respiratory Society β€” European guidelines on nutrition in COPD and chronic respiratory disease; focus on cachexia and nutritional rehabilitation.
  • BTS β€” British Thoracic Society β€” UK protocols on nutrition and ventilatory support; recommendations on energy requirements in respiratory failure.
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  • ACR β€” American College of Rheumatology β€” Guidelines on nutrition and rheumatoid arthritis, gout and lupus; recommendations on omega-3, vitamin D and anti-inflammatory diets.
  • Versus Arthritis (UK) β€” Evidence-based resources on diet and joint inflammation; useful for clinical practice with rheumatology patients.
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  • AISF β€” Associazione Italiana per lo Studio del Fegato β€” Italian reference for NAFLD/MASLD, hepatitis and cirrhosis; nutrition recommendations adapted to the Italian population.
  • AASLD β€” American Association for the Study of Liver Diseases β€” Guidelines on nutrition in cirrhosis, hepatic encephalopathy and transplantation; protein targets and management of hepatic sarcopenia.
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Veterinary field

Reference sources and standards for veterinary nutrition and medicine.

  • NRC (National Research Council) – reference standard for dogs, cats, horses, ruminants
  • FEDIAF (European Pet Food Industry) – dog and cat nutrition guidelines
  • AAFCO – US standards for pet food
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  • WSAVA (World Small Animal Veterinary Association) – general guidelines, vaccines, pet nutrition
  • ESVCN (European Society of Veterinary and Comparative Nutrition)
  • IRIS (International Renal Interest Society) – CKD staging and management in dogs/cats
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  • Diabetes in dogs and cats (ECVIM)
  • Canine hypothyroidism, feline hyperthyroidism (ECVIM)
  • ECVIM β€” European College of Veterinary Internal Medicine β€” Consensus on veterinary endocrinology and nutrition in metabolic disorders (diabetes, hyperadrenocorticism, canine hypothyroidism).
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The listed sources represent the main references on which Cibus AI is trained and updated. The list is constantly evolving and is not exhaustive. Cibus AI is a support tool and does not replace clinical, professional or ethical judgment: every decision remains the full and exclusive responsibility of the professional.